MDMA: Exogamous or Endogenous

Geral T. Blanchard • Dec 05, 2021

Please don’t let the words put you off. They are just scientific ways of saying arising from without or within.

MDMA is a concoction made outside the body that enables people to transcend a somewhat narrow existence of suffering or meaninglessness and rise to an elevated state some might call ecstasy. It is a medicine taken in capsule form. But the question before us is, does our united bodymind have the capacity to make a hormonal, chemical, and spiritual medicine, one that somehow is produced and developed without outside drugs coming into play?

Upon reflection, we know that a healthy microbiome (gut), alive with bacteria fed by prebiotics and probiotics added to a good diet, has an amazing capability. It can produce “medicines of wellbeing.” The intestines are designed to make enkephalins (like the amino acid methionine, or sam-e) and endorphins (opioid peptides), endocannabinoids (weed), serotonin, dopamine, oxytocin, etc.

 So, if we are a living and breathing pharmaceutical storehouse, can we also manufacture MDMA endogenously?

 I think there is a good chance we might just do something much like that. It wouldn’t be much of a stretch given all the other medicines our body manufactures and distributes.


You may recall Abraham Maslow, the renowned psychologist, who long ago wrote about “self-actualization,” unfolding into our newest and best form, and “peak experiences” which can be regarded as transcendent moments with lasting power, not unlike the results of the empathogen MDMA and certain psychedelics. A light bulb comes on that lends deep meaning to many life questions and sets us on a new and more compassionate discovery of life’s meaning and purpose.


When I read the book Quantum Change (2001) by William Miller years ago, I was struck by all of his research participants who reported transcendent awakenings following very intense and long lasting nondrug experiences. I wondered, as did he, what precipitated such events that seemed to come out of the blue. Was it an internal emotional emergency, or what Stanislav Grof would refer to as a “spiritual emergency” that led to an emergent crystallization of a person’s life? Descriptions of the events were very similar to those of MDMA patients and Maslow’s peak experiences. 


At the causal level quantum life changes were not immediately comprehensible to every person. Beyond some events initially being somewhat unpleasant and confounding, certain qualities, in the end, were reported: a) they were profoundly emotional, positive, beneficial, and soothing, b) events, and even material things, seemed more beautiful and brighter thereafter, c) nonjudgmental love swept over them and d) it was like they passed through a one-way door from which there was no turning back – life was unambiguously and positively changed forever. The world was now a bigger and more unified place. Kaboom! Like a clinical MDMA treatment, much of it defied verbal explanation; it was ineffable.


But was there some subtle internal shift going on that might help explain its origins? Maybe something bubbling up from the depths of the psyche and rising to surface awareness under pressure? Miller suggests there was often a hidden or denied crisis festering below conscious awareness. A breaking point was slowly approaching when the internal system had to manufacture a set of internal emotional, and therefore physical changes, to break through. Like a built in survival system, similar to our intestines, a “breakdown” in reverse occurred. It entailed sudden physical and emotional changes, and with it, an enlarged consciousness. Just when they thought they “lost it,” they “got it.”


For Christians it was often described much like a born again experience, or a religious conversion. Others who were more inclined to see themselves as spiritual, described the event as a reset or reboot, much like MDMA patients describe it. It was uniformly seen as a developmental shot forward. And most everyone seems to regard this eye opening experience as sacred because it holds so much personal meaning and offered a sense of deliverance. A new lease on life, a new lens on life.


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“Their [new] spirituality is not isolated, not separate from the rest of their life. Rather it becomes the lens through which they now perceive life.”

- William Miller

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Geral Blanchard, LPC, is a psychotherapist who is university trained in psychology and anthropology. Formerly of Wyoming and currently residing in Iowa, Geral travels the world in search of ancient secrets that can augment the art and science of healing. From Western neuroscience to Amazonian shamanism, he has developed an understanding of how to combine old and new healing strategies to optimize recovery, whether from psychological or physical maladies.


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